Review 'Overall, Organic Chemistry of Drug Degradation is an interesting read and provides the reader with concise information and up-to-date knowledge on chemical as well as analytical aspects of drug degradation.' (Prof. Dr. Mario Thevis, German Sport University Cologne (Germany) ChemMedChem, DOI: 10.1002/cmdc.201300109)'Due to the book?s broad scope and well-balanced coverage of obligatory and new aspects in drug stability research and quality assurance, it is of particular value to students and scientists in the field of pharmaceutical sciences.''The book superbly introduces a broad readership into the arena of drug degradation and impurity testing.' (Prof. Dr. Mario Thevis, German Sport University Cologne (Germany) ChemMedChem, DOI: 10.1002/cmdc.201300109)'...the book provides the interested reader with a comprehensive, overview on all relevant aspects of drug degradation chemistries and analytical strategies.' (Prof. Dr. Mario Thevis, German Sport University Cologne (Germany) ChemMedChem, DOI: 10.1002/cmdc.201300109) Read more Book Description The vast majority of drugs are organic molecular entities. A clear understanding of the chemistry of drug degradation is essential to maintaining the stability, efficacy and safety of medicines throughout their shelf-life. This book examines various degradation pathways with an emphasis on the underlying chemical mechanisms. This approach is essential for degradant identification, formulation development, and manufacturing process improvement. Much of the book is devoted to relevant organic reactions which are reviewed and illustrated with examples. It finishes with a discussion of the strategies for rapid elucidation of drug degradants with regard to the current regulatory requirements and guidelines. This book will be a valuable resource for pharmaceutical and analytical scientists. Read more See all Editorial Reviews
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